GCNT3

Across TCGA cell cohorts, GCNT3 mutation is significantly associated with the mutation status of many other genes, with 968 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GCNT3-associated genes across cancer lineages are PYGL, ADGRF4, and SUZ12. Each is linked with GCNT3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GCNT3-to-partner and partner-to-GCNT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PYGL grouped by GCNT3-low versus GCNT3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCNT3→partner) and Y-score (partner→GCNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PYGL →	+4.392	+4.392	.009	.009	1	3
SKIN	ADGRF4 →	+3.392	+4.718	.002	.002	1	3
BLOOD_Leukemia	SUZ12 →	+4.736	+5.560	.003	.003	1	3
STOMACH	KCNU1 →	+4.807	+4.807	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	SAFB2 →	+4.392	+4.954	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	PLCH2 →	+4.392	+4.954	.008	.008	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 968 associations by consensus.

PYGL by GCNT3 expression — SKIN

Explore this box plot interactively →