GCNT2

Across TCGA cell cohorts, GCNT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,750 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GCNT2-associated GO terms across cancer lineages are Positive regulation of purine nucleotide biosynthetic process, Positive regulation of ATP biosynthetic process, and Positive regulation of nucleotide biosynthetic process. Each is linked with GCNT2 in more than 8 cancer types. Because this analysis shows association rather than direction, both GCNT2-to-partner and partner-to-GCNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of purine nucleotide biosynthetic process grouped by GCNT2-low versus GCNT2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCNT2→partner) and Y-score (partner→GCNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of purine nucleotide biosynthetic process →	+0.137	+0.971	<.001	<.001	3	9
LARGE_INTESTINE	Positive regulation of ATP biosynthetic process →	+0.154	+1.150	<.001	.001	3	9
LARGE_INTESTINE	Positive regulation of nucleotide biosynthetic process →	+0.137	+0.971	<.001	<.001	3	9
BONE	Positive regulation of axon extension →	+0.143	+1.162	.001	.007	3	7
LUNG_NSCLC_LUSC	Response to L-phenylalanine derivative →	+0.147	+2.195	.002	.001	3	6
LARGE_INTESTINE	Indole-containing compound catabolic process →	-0.286	-1.038	<.001	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,750 associations by consensus.

Positive regulation of purine nucleotide biosynthetic process by GCNT2 expression — LARGE_INTESTINE

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