GCNT2

Across TCGA cell cohorts, GCNT2 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GCNT2-associated genes across cancer lineages are GUCA1A, KRTAP10-3, and TREH. Each is linked with GCNT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GCNT2-to-partner and partner-to-GCNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GUCA1A grouped by GCNT2-low versus GCNT2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCNT2→partner) and Y-score (partner→GCNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GUCA1A →	+0.041	+3.426	.002	.007	3	2
CNS	KRTAP10-3 →	+0.021	+5.754	.007	.002	3	2
BLOOD_Myeloma	TREH →	+0.023	+4.807	<.001	.006	3	1
BLOOD_Myeloma	NKAIN3 →	+0.023	+4.807	<.001	.006	3	1
BLOOD_Myeloma	FRRS1L →	+0.040	+4.807	<.001	.006	3	1
BREAST	OR9Q1 →	+0.013	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

GUCA1A by GCNT2 expression — LARGE_INTESTINE

Explore this box plot interactively →