Across TCGA patient cohorts, GCNT1 mutation is significantly associated with the RNA expression of many other genes, with 4,168 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GCNT1-associated genes across cancer lineages are POLE2, AKT1, and ACKR3. Each is linked with GCNT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GCNT1-to-partner and partner-to-GCNT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCNT1→partner) and Y-score (partner→GCNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POLE2 →	+0.393	+2.343	.006	.003	3	3
UCEC	AKT1 →	+0.332	+3.960	.001	<.001	3	3
UCEC	ACKR3 →	-0.761	-2.857	<.001	<.001	3	3
UCEC	PKN3 →	+0.861	+2.868	<.001	<.001	3	3
UCEC	CHAF1A →	+0.785	+3.343	<.001	<.001	3	3
UCEC	SPAG5 →	+0.589	+2.169	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,168 associations by consensus.

Exploration

GCNT1 survival (RNA) · tumor vs normal (RNA) · all GCNT1 data types