Across TCGA cell cohorts, GCNT1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. CNS shows the largest number of these associations.

The most reproducible GCNT1-associated genes across cancer lineages are OR4F15, RBMY1B, and RXFP3. Each is linked with GCNT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GCNT1-to-partner and partner-to-GCNT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCNT1→partner) and Y-score (partner→GCNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR4F15 →	+0.015	+4.977	<.001	.007	3	2
SKIN	RBMY1B →	+1.640	+4.977	<.001	.007	3	1
CNS	RXFP3 →	+0.037	+4.169	.008	.008	3	1
CNS	BTNL2 →	+0.026	+4.169	.007	.008	3	1
LUNG_NSCLC_LUAD	TMEM207 →	+0.095	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

GCNT1 survival (RNA) · tumor vs normal (RNA) · all GCNT1 data types