GCNA

Across TCGA patient cohorts, GCNA RNA expression is significantly associated with the RNA expression of many other genes, with 18,351 significant associations in total. UVM shows the largest number of these associations.

The most reproducible GCNA-associated genes across cancer lineages are AGAP6, DNHD1, and MED8-AS1. Each is linked with GCNA in more than 32 cancer types. Because this analysis shows association rather than direction, both GCNA-to-partner and partner-to-GCNA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCNA versus AGAP6 in SCLC, with a Pearson correlation of 0.80.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCNA→partner) and Y-score (partner→GCNA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	AGAP6 →	+1.442	+1.069	<.001	<.001	3	33
KIRC	DNHD1 →	+1.020	+0.781	<.001	<.001	3	32
KIRC	MED8-AS1 →	+0.819	+0.691	<.001	<.001	3	32
KIRC	UBAP1L →	+1.149	+0.795	<.001	<.001	3	32
UVM	AHSA2P →	+1.814	+0.835	<.001	<.001	3	32
KIRC	SPDYA →	+0.565	+0.784	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,351 associations by consensus.

GCNA vs AGAP6 — SCLC

Explore this scatter interactively →