GCNA

Across TCGA patient cohorts, GCNA RNA expression is significantly associated with the protein abundance of many other proteins, with 8,903 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GCNA-associated proteins across cancer lineages are PATJ_S645, KLF12_S42, and USP16. Each is linked with GCNA in more than 3 cancer types. Because this analysis shows association rather than direction, both GCNA-to-partner and partner-to-GCNA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCNA versus PATJ_S645 in HNSC, with a Pearson correlation of -0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GCNA→partner) and Y-score (partner→GCNA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PATJ_S645 →	-0.297	-0.514	.001	.001	3	4
PDAC	KLF12_S42 →	+1.025	+0.284	<.001	.001	3	3
COAD	USP16 →	-0.202	-0.286	.001	.005	3	3
HNSC	CACNA2D1 →	+0.750	+0.501	<.001	<.001	3	3
COAD	ENGASE →	+0.306	+0.323	<.001	<.001	3	3
GBM	RDH10 →	-0.481	-0.230	.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,903 associations by consensus.

GCNA vs PATJ_S645 — HNSC

Explore this scatter interactively →