GCN1

Across TCGA patient cohorts, GCN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,190 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GCN1-associated proteins across cancer lineages are SRSF9, SART3, and NOL11. Each is linked with GCN1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GCN1-to-partner and partner-to-GCN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCN1 versus SRSF9 in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GCN1→partner) and Y-score (partner→GCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SRSF9 →	+0.435	+0.381	<.001	<.001	3	8
LSCC	SART3 →	+0.253	+0.628	<.001	<.001	3	7
LSCC	NOL11 →	+0.377	+0.534	<.001	<.001	3	7
LSCC	U2SURP →	+0.226	+0.513	<.001	<.001	3	6
LSCC	UTP4 →	+0.370	+0.603	<.001	<.001	3	6
LSCC	SBNO1 →	+0.343	+0.616	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,190 associations by consensus.

GCN1 vs SRSF9 — GBM

Explore this scatter interactively →