GCN1

Across TCGA patient cohorts, GCN1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,270 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GCN1-associated genes across cancer lineages are CNRIP1, F13A1, and RBMS3. Each is linked with GCN1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GCN1-to-partner and partner-to-GCN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCN1 versus CNRIP1 in UCEC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCN1→partner) and Y-score (partner→GCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CNRIP1 →	-0.828	-0.203	<.001	<.001	3	8
HNSC	F13A1 →	-1.548	-0.188	<.001	<.001	3	8
CCRCC	RBMS3 →	-0.703	-0.168	<.001	<.001	3	8
COAD	ZEB1 →	-0.883	-0.213	<.001	<.001	3	8
COAD	LMOD1 →	-1.726	-0.235	<.001	<.001	3	8
CCRCC	CLEC14A →	-1.094	-0.238	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,270 associations by consensus.

GCN1 vs CNRIP1 — UCEC

Explore this scatter interactively →