GCM1

Across TCGA patient cohorts, GCM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,117 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GCM1-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Regulation of double-strand break repair, and Regulation of DNA-templated transcription elongation. Each is linked with GCM1 in more than 21 cancer types. Because this analysis shows association rather than direction, both GCM1-to-partner and partner-to-GCM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by GCM1-low versus GCM1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCM1→partner) and Y-score (partner→GCM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA metabolic process →	+0.062	+0.213	<.001	<.001	3	22
SCLC	Regulation of double-strand break repair →	+0.069	+0.414	<.001	<.001	3	21
STAD	Regulation of DNA-templated transcription elongation →	+0.069	+0.221	<.001	<.001	3	21
STAD	Regulation of DNA repair →	+0.062	+0.214	<.001	<.001	3	20
STAD	DNA-templated transcription elongation →	+0.071	+0.208	<.001	<.001	3	20
ESCA	Regulation of DNA recombination →	+0.072	+0.371	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,117 associations by consensus.

Positive regulation of DNA metabolic process by GCM1 expression — STAD

Explore this box plot interactively →