GCLM

Across TCGA cell cohorts, GCLM RNA expression is significantly associated with the go_rna of many other GO terms, with 4,638 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GCLM-associated GO terms across cancer lineages are Response to thyroxine, Response to human chorionic gonadotropin, and Response to L-phenylalanine derivative. Each is linked with GCLM in more than 18 cancer types. Because this analysis shows association rather than direction, both GCLM-to-partner and partner-to-GCLM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to thyroxine grouped by GCLM-low versus GCLM-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCLM→partner) and Y-score (partner→GCLM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Response to thyroxine →	+0.272	+1.653	<.001	<.001	3	19
LUNG_SCLC	Response to human chorionic gonadotropin →	+0.384	+0.873	.001	<.001	3	19
LIVER	Response to L-phenylalanine derivative →	+0.233	+2.576	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Cellular response to follicle-stimulating hormone stimulus →	+0.378	+2.261	<.001	<.001	3	18
LIVER	Cellular response to hepatocyte growth factor stimulus →	+0.211	+2.759	<.001	<.001	3	18
LIVER	Response to hepatocyte growth factor →	+0.190	+2.669	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,638 associations by consensus.

Response to thyroxine by GCLM expression — OESOPHAGUS

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