GCKR

Across TCGA patient cohorts, GCKR RNA expression is significantly associated with the protein abundance of many other proteins, with 10,012 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GCKR-associated proteins across cancer lineages are C1S, COA7, and CPB2. Each is linked with GCKR in more than 4 cancer types. Because this analysis shows association rather than direction, both GCKR-to-partner and partner-to-GCKR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCKR versus C1S in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GCKR→partner) and Y-score (partner→GCKR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	C1S →	+0.736	+0.243	<.001	<.001	3	5
OV	COA7 →	-0.507	-0.357	.002	.003	3	4
BRCA	CPB2 →	+0.553	+0.168	<.001	.001	3	4
BRCA	P4HA2 →	+0.983	+0.255	<.001	<.001	3	4
BRCA	DST →	+0.514	+0.247	<.001	<.001	3	4
OV	HEPH →	+0.619	+0.211	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,012 associations by consensus.

GCKR vs C1S — BRCA

Explore this scatter interactively →