GCK

Across TCGA patient cohorts, GCK RNA expression is significantly associated with the protein abundance of many other proteins, with 8,128 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GCK-associated proteins across cancer lineages are HYI, SYNPO_S833, and HSPB6. Each is linked with GCK in more than 4 cancer types. Because this analysis shows association rather than direction, both GCK-to-partner and partner-to-GCK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCK versus HYI in BRCA, with a Pearson correlation of 0.07.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GCK→partner) and Y-score (partner→GCK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HYI →	+0.436	+0.086	<.001	.003	2	5
UCEC	SYNPO_S833 →	+0.817	+0.274	.001	.009	3	4
UCEC	HSPB6 →	+0.746	+0.286	.001	.006	3	4
COAD	MRPL11 →	-0.439	-0.067	<.001	.006	3	3
LUAD	MRPL15 →	-0.336	-0.066	.002	<.001	3	3
COAD	MRPL3 →	-0.419	-0.071	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,128 associations by consensus.

GCK vs HYI — BRCA

Explore this scatter interactively →