Across TCGA patient cohorts, GCHFR RNA expression is significantly associated with the go_rna of many other GO terms, with 7,164 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GCHFR-associated GO terms across cancer lineages are Positive regulation of DNA ligation, DTMP metabolic process, and Obsolete neurotransmitter metabolic process. Each is linked with GCHFR in more than 17 cancer types. Because this analysis shows association rather than direction, both GCHFR-to-partner and partner-to-GCHFR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCHFR→partner) and Y-score (partner→GCHFR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of DNA ligation →	+0.059	+0.745	<.001	<.001	3	18
ACC	DTMP metabolic process →	+0.072	+1.651	<.001	<.001	3	17
SCLC	Obsolete neurotransmitter metabolic process →	+0.110	+0.947	<.001	.003	1	18
THYM	Regulation of DNA ligation →	+0.066	+0.723	<.001	.001	3	15
TGCT	Galactose catabolic process →	+0.072	+1.164	<.001	<.001	3	14
THYM	Very long-chain fatty acid catabolic process →	+0.062	+0.948	<.001	<.001	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,164 associations by consensus.

Exploration

GCHFR survival (RNA) · tumor vs normal (RNA) · all GCHFR data types