GCHFR

Across TCGA patient cohorts, GCHFR protein abundance is significantly associated with the RNA expression of many other genes, with 9,813 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GCHFR-associated genes across cancer lineages are ALDH2, TNFSF13, and FBP1. Each is linked with GCHFR in more than 4 cancer types. Because this analysis shows association rather than direction, both GCHFR-to-partner and partner-to-GCHFR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCHFR versus ALDH2 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCHFR→partner) and Y-score (partner→GCHFR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ALDH2 →	+0.668	+0.508	.001	.005	3	5
LUAD	TNFSF13 →	+0.774	+0.444	<.001	<.001	3	5
HNSC	FBP1 →	+1.110	+0.383	<.001	.003	3	5
UCEC	FUCA1 →	+1.027	+0.641	.001	<.001	3	5
GBM	ACP5 →	+0.968	+0.686	<.001	<.001	3	5
CCRCC	HS3ST2 →	+0.896	+0.358	.004	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,813 associations by consensus.

GCHFR vs ALDH2 — UCEC

Explore this scatter interactively →