GCHFR

Across TCGA cell cohorts, GCHFR RNA expression is significantly associated with the go_rna of many other GO terms, with 3,948 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GCHFR-associated GO terms across cancer lineages are Striatal medium spiny neuron differentiation, Establishment of apical/basal cell polarity, and Response to triglyceride. Each is linked with GCHFR in more than 9 cancer types. Because this analysis shows association rather than direction, both GCHFR-to-partner and partner-to-GCHFR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Striatal medium spiny neuron differentiation grouped by GCHFR-low versus GCHFR-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCHFR→partner) and Y-score (partner→GCHFR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Striatal medium spiny neuron differentiation →	-1.242	-2.506	<.001	<.001	3	10
LUNG_SCLC	Establishment of apical/basal cell polarity →	-0.141	-2.649	.007	<.001	2	10
LIVER	Response to triglyceride →	-0.265	-2.982	<.001	<.001	3	9
LIVER	Fatty acid metabolic process →	+0.080	+3.340	.004	.001	3	8
BLOOD_Lymphoma	Negative regulation of actin nucleation →	+0.093	+1.898	.005	.001	3	8
SOFT_TISSUE	Establishment of monopolar cell polarity →	-0.129	-1.961	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,948 associations by consensus.

Striatal medium spiny neuron differentiation by GCHFR expression — STOMACH

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