Across TCGA patient cohorts, GCGR RNA expression is significantly associated with the go_rna of many other GO terms, with 6,909 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GCGR-associated GO terms across cancer lineages are Regulation of binding, Regulation of sphingolipid biosynthetic process, and Proton motive force-driven ATP synthesis. Each is linked with GCGR in more than 13 cancer types. Because this analysis shows association rather than direction, both GCGR-to-partner and partner-to-GCGR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCGR→partner) and Y-score (partner→GCGR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of binding →	+0.074	+0.283	<.001	<.001	3	13
KIRP	Regulation of sphingolipid biosynthetic process →	+0.047	+0.337	<.001	<.001	2	14
HNSC	Proton motive force-driven ATP synthesis →	+0.037	+0.425	<.001	<.001	3	13
STAD	Mitochondrial translation →	+0.086	+0.169	<.001	<.001	2	14
STAD	Mitochondrial gene expression →	+0.085	+0.192	<.001	<.001	2	14
STAD	Protein stabilization →	+0.087	+0.263	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,909 associations by consensus.

Exploration

GCGR survival (RNA) · tumor vs normal (RNA) · all GCGR data types