GCFC2

Across TCGA patient cohorts, GCFC2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,660 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GCFC2-associated genes across cancer lineages are VRK1, NEK2, and CSE1L. Each is linked with GCFC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both GCFC2-to-partner and partner-to-GCFC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCFC2 versus VRK1 in HNSC, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCFC2→partner) and Y-score (partner→GCFC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VRK1 →	+0.844	+0.258	.002	.001	3	5
BRCA	NEK2 →	+1.323	+0.297	<.001	<.001	3	5
BRCA	CSE1L →	+0.535	+0.241	.001	<.001	3	5
BRCA	NUF2 →	+1.165	+0.250	<.001	<.001	3	5
UCEC	TMEM237 →	+0.586	+0.237	<.001	<.001	3	5
HNSC	EXO1 →	+1.119	+0.312	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,660 associations by consensus.

GCFC2 vs VRK1 — HNSC

Explore this scatter interactively →