GCFC2

Across TCGA cell cohorts, GCFC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,397 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GCFC2-associated GO terms across cancer lineages are DNA-templated DNA replication, Chemotaxis, and Taxis. Each is linked with GCFC2 in more than 14 cancer types. Because this analysis shows association rather than direction, both GCFC2-to-partner and partner-to-GCFC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication grouped by GCFC2-low versus GCFC2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCFC2→partner) and Y-score (partner→GCFC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	DNA-templated DNA replication →	+0.101	+0.785	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Chemotaxis →	-0.098	-0.974	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Taxis →	-0.098	-0.974	<.001	<.001	3	15
PANCREAS	Negative regulation of defense response →	-0.059	-0.710	.002	.001	3	14
LUNG_NSCLC_LUSC	Regulation of tumor necrosis factor superfamily cytokine production →	-0.099	-0.713	<.001	.004	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cytokine-mediated signaling pathway →	-0.101	-0.710	<.001	.008	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,397 associations by consensus.

DNA-templated DNA replication by GCFC2 expression — OVARY

Explore this box plot interactively →