GBX2

Across TCGA cell cohorts, GBX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,508 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GBX2-associated GO terms across cancer lineages are Diadenosine polyphosphate metabolic process, Transcription initiation at RNA polymerase II promoter, and Positive regulation of mitotic cell cycle phase transition. Each is linked with GBX2 in more than 8 cancer types. Because this analysis shows association rather than direction, both GBX2-to-partner and partner-to-GBX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Diadenosine polyphosphate metabolic process grouped by GBX2-low versus GBX2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GBX2→partner) and Y-score (partner→GBX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Diadenosine polyphosphate metabolic process →	-0.137	-1.482	.002	.006	3	8
URINARY_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.065	+1.268	.001	.006	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitotic cell cycle phase transition →	+0.064	+0.610	.002	.001	3	8
SKIN	Positive regulation of sodium ion transport →	-0.186	-0.630	<.001	.003	3	8
URINARY_TRACT	Negative regulation of bone mineralization involved in bone maturation →	+1.699	+1.381	<.001	.003	3	7
OESOPHAGUS	Nuclear transport →	+0.082	+1.028	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,508 associations by consensus.

Diadenosine polyphosphate metabolic process by GBX2 expression — BONE

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