Across TCGA patient cohorts, GBP7 protein abundance is significantly associated with the RNA expression of many other genes, with 2,705 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GBP7-associated genes across cancer lineages are GBP4, TAF5LP1, and APOL3. Each is linked with GBP7 in more than 3 cancer types. Because this analysis shows association rather than direction, both GBP7-to-partner and partner-to-GBP7 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP7→partner) and Y-score (partner→GBP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GBP4 →	+1.694	+1.079	<.001	<.001	3	4
UCEC	TAF5LP1 →	+1.028	+1.341	.001	<.001	3	4
BRCA	APOL3 →	+0.744	+1.024	.002	<.001	3	4
BRCA	CD3G →	+0.905	+1.189	<.001	<.001	3	3
CCRCC	FCRL3 →	+0.830	+1.009	<.001	<.001	3	3
UCEC	ARHGAP25 →	+0.701	+0.909	.003	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,705 associations by consensus.

Exploration

GBP7 survival (RNA) · tumor vs normal (RNA) · all GBP7 data types