GBP7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GBP7 mutation is significantly associated with the RNA expression of many other genes, with 2,079 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GBP7-associated genes across cancer lineages are LINC02249, RNA5SP55, and OSBPL9P5. Each is linked with GBP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both GBP7-to-partner and partner-to-GBP7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP7→partner) and Y-score (partner→GBP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READLINC02249 →+0.042+5.219<.001.00632
COADRNA5SP55 →+0.442+4.790<.001<.00132
COADOSBPL9P5 →+0.300+5.734<.001<.00132
UCECBAP1 →+0.276+1.807.008.00432
UCECH2AZ1 →+0.599+2.169<.001<.00132
UCECPLK1 →+0.592+2.518.006.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,079 associations by consensus.

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