Across TCGA cell cohorts, GBP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,301 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GBP7-associated GO terms across cancer lineages are Negative regulation of non-canonical NF-kappaB signal transduction, Regulation of pattern recognition receptor signaling pathway, and Cellular response to chemical stress. Each is linked with GBP7 in more than 5 cancer types. Because this analysis shows association rather than direction, both GBP7-to-partner and partner-to-GBP7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP7→partner) and Y-score (partner→GBP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of non-canonical NF-kappaB signal transduction →	+0.071	+0.043	.001	<.001	3	6
CNS	Regulation of pattern recognition receptor signaling pathway →	+0.040	+0.057	<.001	<.001	3	6
BLOOD_Lymphoma	Cellular response to chemical stress →	+0.026	+0.039	.006	.009	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of response to cytokine stimulus →	+0.071	+0.067	<.001	.002	3	5
BLOOD_Leukemia	Negative regulation of lymphoid progenitor cell differentiation →	+0.151	+0.051	<.001	.005	3	5
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cytokine-mediated signaling pathway →	+0.091	+0.064	.004	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,301 associations by consensus.

Exploration

GBP7 survival (RNA) · tumor vs normal (RNA) · all GBP7 data types