Across TCGA patient cohorts, GBP6 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,241 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GBP6-associated proteins across cancer lineages are OAS2, SAMD9, and UBE2L6. Each is linked with GBP6 in more than 4 cancer types. Because this analysis shows association rather than direction, both GBP6-to-partner and partner-to-GBP6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP6→partner) and Y-score (partner→GBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OAS2 →	+0.530	+0.248	<.001	<.001	3	5
BRCA	SAMD9 →	+0.631	+0.452	<.001	<.001	3	5
COAD	UBE2L6 →	+0.566	+0.209	<.001	<.001	3	5
OV	GBP2 →	+0.569	+0.460	<.001	.003	3	5
BRCA	HLA-F →	+0.478	+0.311	<.001	<.001	3	5
LSCC	VSNL1 →	+1.045	+2.260	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,241 associations by consensus.

Exploration

GBP6 survival (RNA) · tumor vs normal (RNA) · all GBP6 data types