Across TCGA patient cohorts, GBP6 protein abundance is significantly associated with the RNA expression of many other genes, with 8,377 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GBP6-associated genes across cancer lineages are TACSTD2, CAPNS1P1, and TGM5. Each is linked with GBP6 in more than 3 cancer types. Because this analysis shows association rather than direction, both GBP6-to-partner and partner-to-GBP6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP6→partner) and Y-score (partner→GBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TACSTD2 →	+1.181	+0.615	.006	.005	3	4
LSCC	CAPNS1P1 →	+1.841	+1.919	<.001	<.001	3	4
HNSC	TGM5 →	+1.342	+0.827	<.001	<.001	3	3
HNSC	HDHD3 →	+0.775	+0.699	.001	<.001	3	3
HNSC	CSTA →	+2.069	+0.847	<.001	<.001	3	3
HNSC	IPPK →	+0.861	+0.546	.002	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,377 associations by consensus.

Exploration

GBP6 survival (RNA) · tumor vs normal (RNA) · all GBP6 data types