Across TCGA patient cohorts, GBP6 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,088 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GBP6-associated proteins across cancer lineages are NFKBIE, ANXA1, and CLCA4. Each is linked with GBP6 in more than 2 cancer types. Because this analysis shows association rather than direction, both GBP6-to-partner and partner-to-GBP6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP6→partner) and Y-score (partner→GBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NFKBIE →	-0.532	-1.283	<.001	<.001	3	3
HNSC	ANXA1 →	+0.690	+0.737	<.001	<.001	3	3
LSCC	CLCA4 →	+1.031	+0.778	.001	.003	3	3
LSCC	BICD2 →	+0.592	+1.449	<.001	<.001	3	3
LSCC	DSG3 →	+1.773	+1.716	<.001	<.001	3	3
HNSC	EPB41L1_S639 →	+0.906	+0.583	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,088 associations by consensus.

Exploration

GBP6 survival (RNA) · tumor vs normal (RNA) · all GBP6 data types