Across TCGA patient cohorts, GBP6 mutation is significantly associated with the RNA expression of many other genes, with 2,066 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GBP6-associated genes across cancer lineages are MRPL51P2, RNU6-1131P, and MTND2P8. Each is linked with GBP6 in more than 2 cancer types. Because this analysis shows association rather than direction, both GBP6-to-partner and partner-to-GBP6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP6→partner) and Y-score (partner→GBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	MRPL51P2 →	+0.122	+3.902	.005	.007	3	3
SKCM	RNU6-1131P →	+0.074	+4.910	<.001	.001	3	3
CESC	MTND2P8 →	+0.046	+5.418	<.001	.005	3	2
SKCM	RN7SL351P →	+0.154	+1.862	.005	.008	3	2
HNSC	RNA5SP53 →	+0.410	+5.015	<.001	.009	3	2
UCEC	EME1 →	+0.499	+1.673	.004	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,066 associations by consensus.

Exploration

GBP6 survival (RNA) · tumor vs normal (RNA) · all GBP6 data types