GBP5

Across TCGA patient cohorts, GBP5 protein abundance is significantly associated with the RNA expression of many other genes, with 15,676 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GBP5-associated genes across cancer lineages are CYTH4, ETV7, and CSF2RB. Each is linked with GBP5 in more than 9 cancer types. Because this analysis shows association rather than direction, both GBP5-to-partner and partner-to-GBP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GBP5 versus CYTH4 in GBM, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP5→partner) and Y-score (partner→GBP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+1.259	+0.925	<.001	<.001	3	10
OV	ETV7 →	+1.826	+1.102	<.001	<.001	3	10
OV	CSF2RB →	+1.430	+0.970	<.001	<.001	3	10
BRCA	IL2RB →	+1.229	+1.044	<.001	<.001	3	10
OV	GZMH →	+1.657	+0.845	<.001	<.001	3	10
BRCA	SLA2 →	+1.065	+1.087	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,676 associations by consensus.

GBP5 vs CYTH4 — GBM

Explore this scatter interactively →