GBP3

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GBP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,762 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GBP3-associated proteins across cancer lineages are UBE2L6, NMI, and PSMB10. Each is linked with GBP3 in more than 8 cancer types. Because this analysis shows association rather than direction, both GBP3-to-partner and partner-to-GBP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GBP3 versus UBE2L6 in HNSC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP3→partner) and Y-score (partner→GBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCUBE2L6 →+0.680+0.880<.001<.00139
OVNMI →+0.564+1.646<.001<.00138
HNSCPSMB10 →+0.458+0.840<.001<.00138
OVPSMB5 →-0.471-1.116.004.00338
HNSCDDX60 →+0.634+0.893<.001<.00138
HNSCGBP4 →+0.781+1.111<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,762 associations by consensus.

GBP3 vs UBE2L6 — HNSC

Per-sample scatter of GBP3 vs UBE2L6 in HNSC (Pearson r = 0.40).

Explore this scatter interactively →

Exploration