GBP3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GBP3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,976 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GBP3-associated genes across cancer lineages are DAZAP1, TIPIN, and ATAT1. Each is linked with GBP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GBP3-to-partner and partner-to-GBP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GBP3 versus DAZAP1 in UCEC, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP3→partner) and Y-score (partner→GBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECDAZAP1 →-0.447-0.461<.001.00132
OVTIPIN →-0.644-0.565.006.00632
UCECATAT1 →-0.473-0.339.002.00232
UCECADRB2 →+1.003+0.325<.001.00432
UCECULK1 →-0.423-0.441.009.00232
GBMAPOBR →+0.878+1.290.008.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,976 associations by consensus.

GBP3 vs DAZAP1 — UCEC

Per-sample scatter of GBP3 vs DAZAP1 in UCEC (Pearson r = -0.44).

Explore this scatter interactively →

Exploration