GBP2

Across TCGA cell cohorts, GBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,923 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GBP2-associated GO terms across cancer lineages are Cytolysis in another organism, Type II interferon-mediated signaling pathway, and Negative regulation of cell adhesion. Each is linked with GBP2 in more than 18 cancer types. Because this analysis shows association rather than direction, both GBP2-to-partner and partner-to-GBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytolysis in another organism grouped by GBP2-low versus GBP2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP2→partner) and Y-score (partner→GBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Cytolysis in another organism →	+1.995	+4.010	<.001	<.001	3	19
BREAST	Type II interferon-mediated signaling pathway →	+0.216	+2.057	<.001	<.001	3	16
KIDNEY	Negative regulation of cell adhesion →	+0.081	+2.019	.003	.003	3	16
LUNG_NSCLC_LUSC	Regulation of proteolysis →	+0.119	+3.251	<.001	<.001	3	15
LIVER	Response to protozoan →	+1.277	+3.423	.006	.001	3	15
LIVER	Defense response to protozoan →	+1.277	+3.423	.006	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,923 associations by consensus.

Cytolysis in another organism by GBP2 expression — LIVER

Explore this box plot interactively →