Across TCGA patient cohorts, GBP1P1 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GBP1P1-associated genes across cancer lineages are Ku80, Notch1, and Rab25. Each is linked with GBP1P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GBP1P1-to-partner and partner-to-GBP1P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP1P1→partner) and Y-score (partner→GBP1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.250	+1.887	.023	.031	3	1
UCEC	Notch1 →	+0.248	+3.183	<.001	.009	3	1
UCEC	Rab25 →	-0.440	-2.584	.004	.011	3	1
UCEC	Stathmin →	+0.208	+2.833	.001	.034	3	1
UCEC	BRD4 →	+0.388	+2.466	.002	.011	3	1
UCEC	4E-BP1 →	+0.337	+2.199	.007	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

GBP1P1 survival (RNA) · tumor vs normal (RNA) · all GBP1P1 data types