GBP1

Across TCGA patient cohorts, GBP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,282 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GBP1-associated proteins across cancer lineages are STAT1, TAP2, and CMPK2. Each is linked with GBP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both GBP1-to-partner and partner-to-GBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GBP1 versus STAT1 in LSCC, with a Pearson correlation of 0.82.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP1→partner) and Y-score (partner→GBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	STAT1 →	+0.804	+1.267	<.001	<.001	3	10
BRCA	TAP2 →	+0.790	+1.349	<.001	<.001	3	10
GBM	CMPK2 →	+0.807	+1.272	<.001	<.001	3	10
HNSC	GBP2 →	+0.739	+1.720	<.001	<.001	3	10
HNSC	GBP4 →	+0.877	+1.611	<.001	<.001	3	10
HNSC	GBP5 →	+1.229	+1.584	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,282 associations by consensus.

GBP1 vs STAT1 — LSCC

Explore this scatter interactively →