GBP1

Across TCGA patient cohorts, GBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,370 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GBP1-associated genes across cancer lineages are ETV7, SAMHD1, and TNFSF13B. Each is linked with GBP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both GBP1-to-partner and partner-to-GBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GBP1 versus ETV7 in BRCA, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP1→partner) and Y-score (partner→GBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ETV7 →	+1.551	+0.966	<.001	<.001	3	10
HNSC	SAMHD1 →	+0.843	+0.826	<.001	<.001	3	10
COAD	TNFSF13B →	+0.972	+0.707	<.001	<.001	3	10
UCEC	OAS2 →	+1.405	+0.662	<.001	.003	3	10
LSCC	STAT1 →	+1.225	+0.834	<.001	<.001	3	10
GBM	IFIT3 →	+1.455	+0.790	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,370 associations by consensus.

GBP1 vs ETV7 — BRCA

Explore this scatter interactively →