GBP1

Across TCGA cell cohorts, GBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,971 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible GBP1-associated GO terms across cancer lineages are Cytolysis in another organism, Antigen processing and presentation of exogenous peptide antigen via MHC class Ib, and Antigen processing and presentation of endogenous antigen. Each is linked with GBP1 in more than 17 cancer types. Because this analysis shows association rather than direction, both GBP1-to-partner and partner-to-GBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytolysis in another organism grouped by GBP1-low versus GBP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP1→partner) and Y-score (partner→GBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cytolysis in another organism →	+2.016	+3.130	<.001	<.001	3	18
BREAST	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	+0.270	+2.997	<.001	<.001	3	16
BREAST	Antigen processing and presentation of endogenous antigen →	+0.322	+3.141	<.001	<.001	3	15
BREAST	Negative regulation of response to biotic stimulus →	+0.094	+2.728	<.001	<.001	3	15
PANCREAS	CD8-positive, alpha-beta T cell activation →	+0.159	+1.879	<.001	<.001	3	15
CNS	Positive regulation of canonical NF-kappaB signal transduction →	+0.067	+2.215	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,971 associations by consensus.

Cytolysis in another organism by GBP1 expression — BONE

Explore this box plot interactively →