GBGT1

Across TCGA cell cohorts, GBGT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,536 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GBGT1-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Regulation of protein localization to Cajal body, and Positive regulation of protein localization to Cajal body. Each is linked with GBGT1 in more than 11 cancer types. Because this analysis shows association rather than direction, both GBGT1-to-partner and partner-to-GBGT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by GBGT1-low versus GBGT1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GBGT1→partner) and Y-score (partner→GBGT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.179	+2.212	<.001	<.001	3	12
OESOPHAGUS	Regulation of protein localization to Cajal body →	+0.107	+2.086	<.001	.001	3	12
OESOPHAGUS	Positive regulation of protein localization to Cajal body →	+0.107	+2.086	<.001	.001	3	12
BREAST	Axoneme assembly →	-0.054	-1.222	<.001	<.001	3	11
SOFT_TISSUE	Protein targeting to ER →	+0.106	+1.518	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Negative regulation of respiratory burst involved in inflammatory response →	+0.067	+0.603	.002	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,536 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by GBGT1 expression — OESOPHAGUS

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