GBF1

Across TCGA patient cohorts, GBF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,631 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GBF1-associated proteins across cancer lineages are RIF1_S1454, SLC38A1_S52, and ABLIM1_S367. Each is linked with GBF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both GBF1-to-partner and partner-to-GBF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GBF1 versus RIF1_S1454 in BRCA, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GBF1→partner) and Y-score (partner→GBF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RIF1_S1454 →	-0.956	-0.677	<.001	<.001	3	3
UCEC	SLC38A1_S52 →	-0.834	-0.368	<.001	<.001	2	4
PDAC	ABLIM1_S367 →	+0.825	+0.338	.001	<.001	3	3
OV	AFG3L2 →	-0.411	-0.796	<.001	.003	3	3
UCEC	SEC24C →	+0.222	+0.469	<.001	<.001	3	3
BRCA	BRD4_S1126 →	-0.510	-0.370	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,631 associations by consensus.

GBF1 vs RIF1_S1454 — BRCA

Explore this scatter interactively →