GBF1

Across TCGA patient cohorts, GBF1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,315 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GBF1-associated genes across cancer lineages are CEP68, ZBTB26, and SECISBP2. Each is linked with GBF1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GBF1-to-partner and partner-to-GBF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GBF1 versus CEP68 in LSCC, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GBF1→partner) and Y-score (partner→GBF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CEP68 →	-0.573	-0.221	<.001	<.001	3	7
LSCC	ZBTB26 →	-0.632	-0.152	<.001	<.001	3	7
OV	SECISBP2 →	-0.487	-0.193	.007	.004	3	7
UCEC	SNHG20 →	-0.545	-0.174	.001	.001	3	6
HNSC	ZNF302 →	-0.766	-0.171	<.001	<.001	3	6
HNSC	KAT2A →	-0.791	-0.187	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,315 associations by consensus.

GBF1 vs CEP68 — LSCC

Explore this scatter interactively →