GBE1

Across TCGA patient cohorts, GBE1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,990 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GBE1-associated proteins across cancer lineages are PLOD2, ITGA5, and P4HA2. Each is linked with GBE1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GBE1-to-partner and partner-to-GBE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GBE1 versus PLOD2 in PDAC, with a Pearson correlation of 0.79.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GBE1→partner) and Y-score (partner→GBE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PLOD2 →	+1.074	+0.748	<.001	<.001	3	7
PDAC	ITGA5 →	+0.626	+0.630	<.001	<.001	3	7
PDAC	P4HA2 →	+0.912	+0.745	<.001	<.001	3	6
COAD	PKM →	+0.372	+0.430	<.001	<.001	3	6
GBM	PLOD1 →	+0.671	+0.777	<.001	<.001	3	6
OV	LDHA →	+0.409	+0.584	.004	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,990 associations by consensus.

GBE1 vs PLOD2 — PDAC

Explore this scatter interactively →