GBE1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GBE1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,066 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GBE1-associated genes across cancer lineages are TSHZ3, PLOD2, and LNCSRLR. Each is linked with GBE1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GBE1-to-partner and partner-to-GBE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GBE1 versus TSHZ3 in BRCA, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GBE1→partner) and Y-score (partner→GBE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCATSHZ3 →+0.885+0.401<.001<.00137
PDACPLOD2 →+1.154+0.380<.001<.00137
PDACLNCSRLR →+0.978+0.323<.001<.00137
COADHIF1A-AS3 →+1.030+0.397<.001<.00137
COADVIM →+0.882+0.371<.001<.00137
OVENO2 →+1.329+0.344.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,066 associations by consensus.

GBE1 vs TSHZ3 — BRCA

Per-sample scatter of GBE1 vs TSHZ3 in BRCA (Pearson r = 0.38).

Explore this scatter interactively →

Exploration