GBE1

Across TCGA cell cohorts, GBE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,467 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GBE1-associated GO terms across cancer lineages are Polysaccharide biosynthetic process, Positive regulation of focal adhesion assembly, and Glycogen biosynthetic process. Each is linked with GBE1 in more than 12 cancer types. Because this analysis shows association rather than direction, both GBE1-to-partner and partner-to-GBE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Polysaccharide biosynthetic process grouped by GBE1-low versus GBE1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GBE1→partner) and Y-score (partner→GBE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Polysaccharide biosynthetic process →	+0.125	+2.235	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Positive regulation of focal adhesion assembly →	+0.202	+1.437	<.001	<.001	3	12
BONE	Glycogen biosynthetic process →	+0.107	+3.126	<.001	<.001	3	12
BONE	Glucan biosynthetic process →	+0.107	+3.126	<.001	<.001	3	12
BREAST	Positive regulation of extracellular matrix organization →	+0.199	+1.838	<.001	<.001	3	12
BONE	Regulation of cell-substrate junction assembly →	+0.159	+3.050	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,467 associations by consensus.

Polysaccharide biosynthetic process by GBE1 expression — BONE

Explore this box plot interactively →