GBA2

Across TCGA patient cohorts, GBA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,632 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GBA2-associated proteins across cancer lineages are BAG1, VCP, and UNC13B. Each is linked with GBA2 in more than 6 cancer types. Because this analysis shows association rather than direction, both GBA2-to-partner and partner-to-GBA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GBA2 versus BAG1 in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GBA2→partner) and Y-score (partner→GBA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BAG1 →	+0.374	+0.692	<.001	<.001	3	7
PDAC	VCP →	+0.397	+0.825	<.001	<.001	3	5
LUAD	UNC13B →	+0.376	+0.303	.002	.005	2	6
LSCC	STOML2 →	+0.584	+0.607	<.001	<.001	3	5
LSCC	SMU1 →	+0.213	+0.493	<.001	<.001	3	5
GBM	APTX →	+0.351	+0.505	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,632 associations by consensus.

GBA2 vs BAG1 — LSCC

Explore this scatter interactively →