GATM

Across TCGA pan-cancer cohorts, GATM mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GATM data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher GATM mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GATM expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

COAD, CCRCC, and UCEC are the cancer types where GATM mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.918	1.000	.012	84	view →
CCRCC	OS	Median	IV	0.785	0.123	.009	23	view →
UCEC	DFS	Quartile	III,IV	0.398	1.000	.040	8	view →
HNSC	DFS	Median	II,III,IV	0.573	0.753	.036	5	view →
PDAC	OS	Tertile	IV	0.231	0.905	.024	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

GATM–COAD (DFS)

Open the COAD breakdown →