GATM

Across TCGA patient cohorts, GATM protein abundance is significantly associated with the RNA expression of many other genes, with 7,794 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GATM-associated genes across cancer lineages are HOXD3, CYP4X1, and PTGER3. Each is linked with GATM in more than 2 cancer types. Because this analysis shows association rather than direction, both GATM-to-partner and partner-to-GATM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GATM versus HOXD3 in UCEC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GATM→partner) and Y-score (partner→GATM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HOXD3 →	-0.724	-0.602	<.001	.001	3	3
BRCA	CYP4X1 →	+2.364	+0.510	<.001	.005	3	3
UCEC	PTGER3 →	-1.060	-0.655	<.001	<.001	3	3
LUAD	RRM2 →	-0.903	-0.465	<.001	.004	3	3
LSCC	NPM1P9 →	-0.369	-0.358	.002	.002	3	3
LSCC	SNHG18 →	+1.010	+0.560	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,794 associations by consensus.

GATM vs HOXD3 — UCEC

Explore this scatter interactively →