GATM

Across TCGA cell cohorts, GATM RNA expression is significantly associated with the go_rna of many other GO terms, with 4,037 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GATM-associated GO terms across cancer lineages are Nucleotide biosynthetic process, Blood vessel morphogenesis, and Negative regulation of mRNA metabolic process. Each is linked with GATM in more than 8 cancer types. Because this analysis shows association rather than direction, both GATM-to-partner and partner-to-GATM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide biosynthetic process grouped by GATM-low versus GATM-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GATM→partner) and Y-score (partner→GATM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleotide biosynthetic process →	+0.096	+1.599	<.001	.008	3	9
BONE	Blood vessel morphogenesis →	-0.081	-1.521	<.001	<.001	3	8
SOFT_TISSUE	Negative regulation of mRNA metabolic process →	+0.080	+2.857	<.001	.001	3	8
BLOOD_Lymphoma	Regulation of syncytium formation by plasma membrane fusion →	+0.074	+1.719	.001	.009	3	8
BLOOD_Leukemia	Mitochondrial electron transport, NADH to ubiquinone →	+0.083	+1.385	<.001	.002	3	8
BONE	Granzyme-mediated apoptotic signaling pathway →	+0.103	+1.584	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,037 associations by consensus.

Nucleotide biosynthetic process by GATM expression — BONE

Explore this box plot interactively →