GATD1

Across TCGA pan-cancer cohorts, GATD1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated GATD1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher GATD1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GATD1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

COAD, CCRCC, and HNSC are the cancer types where GATD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.879	1.000	.018	42	view →
CCRCC	OS	Median	III,IV	0.890	0.520	.004	22	view →
HNSC	DFS	Median	III,IV	0.880	0.701	.005	18	view →
LUAD	OS	Median	All	0.915	0.999	.006	14	view →
UCEC	DFS	Quartile	II,III,IV	0.211	0.798	.029	10	view →
LSCC	DFS	Median	III,IV	0.882	1.000	.048	2	view →
PDAC	DFS	Quartile	All	0.936	0.765	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GATD1–COAD (DFS)

Open the COAD breakdown →