GATD1

Across TCGA patient cohorts, GATD1 RNA expression is significantly associated with the mutation status of many other genes, with 8,874 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GATD1-associated genes across cancer lineages are KRAS, EGFR, and TP53. Each is linked with GATD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GATD1-to-partner and partner-to-GATD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRAS grouped by GATD1-low versus GATD1-high in UCEC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GATD1→partner) and Y-score (partner→GATD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KRAS →	+1.140	+0.198	.004	.002	3	5
LGG	EGFR →	+2.523	+0.406	<.001	<.001	3	4
LIHC	TP53 →	+1.175	+0.311	<.001	<.001	3	4
UCEC	OBSCN →	+0.801	+0.298	<.001	<.001	3	4
PRAD	MUC16 →	+2.175	+0.277	.002	<.001	3	3
LIHC	SPEG →	+2.608	+0.473	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,874 associations by consensus.

KRAS by GATD1 expression — UCEC

Explore this box plot interactively →