GATD1

Across TCGA cell cohorts, GATD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,810 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GATD1-associated GO terms across cancer lineages are Methylglyoxal metabolic process, Response to methylglyoxal, and Cellular response to methylglyoxal. Each is linked with GATD1 in more than 19 cancer types. Because this analysis shows association rather than direction, both GATD1-to-partner and partner-to-GATD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methylglyoxal metabolic process grouped by GATD1-low versus GATD1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GATD1→partner) and Y-score (partner→GATD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Methylglyoxal metabolic process →	+0.175	+1.059	<.001	.002	3	20
UPPER_AERODIGESTIVE_TRACT	Response to methylglyoxal →	+0.189	+1.764	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Cellular response to methylglyoxal →	+0.189	+1.764	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Cellular detoxification of methylglyoxal →	+0.189	+1.764	<.001	<.001	3	20
LUNG_NSCLC_LUSC	Methylglyoxal catabolic process →	+0.205	+1.675	<.001	<.001	3	19
BONE	Pre-mRNA catabolic process →	+0.229	+1.148	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,810 associations by consensus.

Methylglyoxal metabolic process by GATD1 expression — STOMACH

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