GATD1

Across TCGA cell cohorts, GATD1 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GATD1-associated genes across cancer lineages are ADAM7, DAZ4, and EPPIN. Each is linked with GATD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GATD1-to-partner and partner-to-GATD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAM7 grouped by GATD1-low versus GATD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GATD1→partner) and Y-score (partner→GATD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ADAM7 →	+0.035	+4.922	<.001	.009	3	2
LARGE_INTESTINE	DAZ4 →	+0.326	+4.977	<.001	.007	3	1
BLOOD_Leukemia	EPPIN →	+0.006	+4.922	.005	.009	3	1
BLOOD_Leukemia	GPR26 →	+0.077	+5.539	<.001	.003	3	1
BLOOD_Leukemia	SCGB3A2 →	+0.144	+4.922	<.001	.009	3	1
BLOOD_Leukemia	NKX2-6 →	+0.639	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

ADAM7 by GATD1 expression — BLOOD_Leukemia

Explore this box plot interactively →