GATAD2B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GATAD2B mutation is significantly associated with the RNA expression of many other genes, with 4,186 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GATAD2B-associated genes across cancer lineages are HNRNPH1P2, FAM151B, and FBXO36. Each is linked with GATAD2B in more than 1 cancer types. Because this analysis shows association rather than direction, both GATAD2B-to-partner and partner-to-GATAD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HNRNPH1P2 grouped by GATAD2B-low versus GATAD2B-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GATAD2B→partner) and Y-score (partner→GATAD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCHNRNPH1P2 →+0.059+5.060<.001.00132
UCECFAM151B →+0.293+2.319<.001<.00132
UCECFBXO36 →+0.389+2.098.008.00232
UCECNCK1 →+0.473+2.534.001<.00132
UCECABHD3 →+0.774+2.443<.001<.00132
UCECCHAF1B →+0.574+3.906<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,186 associations by consensus.

HNRNPH1P2 by GATAD2B expression — CESC

Box plot of HNRNPH1P2 in GATAD2B-low vs GATAD2B-high samples in CESC.

Explore this box plot interactively →

Exploration